Video: Dab tsi ua rau sab laug hloov pauv hauv oxyhemoglobin nkhaus?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Sab laug ua haujlwm ntawm nkhaus yog ib lub cim ntawm hemoglobin cov nce affinity rau oxygen (piv txwv li ntawm lub ntsws). fetal hemoglobin muaj dua O2 kev sib raug zoo dua li neeg laus hemoglobin ; Feem ntau yog vim qhov txo qis affinity rau 2, 3-bisphosphoglycerate.
Hais txog qhov no, dab tsi ua rau kev hloov pauv sab laug ntawm txoj kab nkhaus kev sib cais oxygen?
Qhov kub thiab txias nce ntxiv ua haujlwm cov nkhaus mus rau sab xis, thaum qhov kub tau txo qis ua haujlwm cov nkhaus mus rau sab laug . Ua kom qhov kub tsis sib xws sib luag ntawm oxygen thiab hemoglobin, uas ua rau nce nyiaj ntau oxygen thiab hemoglobin thiab txo qis cov concentration ntawm oxyhaemoglobin.
Tom qab ntawd, lo lus nug yog, qhov nkhaus ntawm kev sib cais oxyhemoglobin qhia dab tsi rau peb? Cov oxyhemoglobin dissociation nkhaus (OHDC) qhia txog kev sib raug zoo ntawm oxygen saturation ntawm hemoglobin (Soj2) thiab ib nrab siab ntawm cov hlab ntsha oxygen (Pao2). Nws indirectly qhia arterial hemoglobin saturation, ntsuas raws li oxygen saturation los ntawm mem tes oximetry (Spo2).
Ua li no, leej twg ntawm cov hauv qab no hloov oxyhemoglobin dissociation nkhaus mus rau sab laug?
Kev hloov pauv hauv plasma pH tuaj yeem ua rau a ua haujlwm hauv nkhaus rau sab laug lossis txoj cai nyob ntawm qhov tshwm sim pH. Yog hais tias pH ua ntau acidic, lub nkhaus hloov mus rau sab xis. Hauv kev teeb tsa ntau alkaline plasma pH, tus oxygen – hemoglobin dissociation nkhaus hloov pauv mus rau sab laug.
Dab tsi yog qhov cuam tshuam ntawm hypothermia ntawm txoj kab nkhaus kev sib cais oxyhemoglobin?
Kev txo lub cev kub (hypothermia) ua rau sab laug ua haujlwm nyob rau hauv qhov nkhaus kev sib cais oxyhemoglobin, piv txwv li nce hemoglobin kev sib raug zoo rau cov pa, qhov nce ntawm lub cev kub (hyperthermia) ua rau sab xis ua haujlwm , i.e. txo hemoglobin affinity rau oxygen [8].
Pom zoo:
Dab tsi yog txoj haujlwm ntawm sab laug sab laug sab laug?
Hauv tib neeg feem ntau, sab laug ntawm lub paj hlwb yog qhov tseem ceeb, thiab hauv tib neeg feem ntau sab laug sab laug sab laug tswj kev nco txog ntsig txog qhov tseeb thiab cov ntaub ntawv, nrog rau lub peev xwm paub lub ntsej muag thiab khoom
Dab tsi yog kev hloov pauv sab laug hauv qhov nkhaus sib cais oxyhemoglobin hu ua?
Cov xwm txheej no hloov pauv lossis hloov pauv qhov nkhaus ntawm kev sib cais oxyhemoglobin. Kev hloov pauv sab xis qhia tias hemoglobin hauv kev tshawb fawb tau txo qis kev nyiam rau oxygen. Kev ua haujlwm sab laug ntawm txoj kab nkhaus yog ib qho cim ntawm hemoglobin kev sib raug zoo ntxiv rau oxygen (piv txwv li ntawm lub ntsws)
Dab tsi ua rau oxyhemoglobin dissociation nkhaus hloov?
Kev nce siab ntxiv ntawm BPG hauv cov qe ntshav liab nyiam qhov tsim ntawm T, qis qis hauv lub xeev ntawm hemoglobin thiab yog li cov pa nkev-khi nkhaus yuav hloov mus rau sab xis
Qhov kev hloov pauv twg yuav ua rau hloov mus rau sab laug hauv cov pa oxygen hemoglobin khi nkhaus?
Cov pa -hemoglobin kev sib cais sib cais tuaj yeem txav chaw xws li qhov kev sib raug zoo rau cov pa oxygen tau hloov pauv. Cov yam ntxwv uas hloov qhov nkhaus muaj xws li kev hloov pauv hauv cov pa roj carbon dioxide concentration, ntshav kub, ntshav pH, thiab cov concentration ntawm 2,3-diphosphoglycerate (2,3-DPG)
Dab tsi hloov pauv tshwm sim hauv cov kua dej sab hauv thiab sab hauv lub cev thaum lub cev qhuav dej?
Cov ntsev ntau hauv dej, siab dua osmotic siab. Raws li qhov xwm txheej ib txwm muaj, osmotic siab nyob rau hauv qhov chaw tso rau sab hauv yog zoo ib yam li hauv qhov chaw sab nrauv. Thaum lub cev qhuav dej tshwm sim, txawm li cas los xij, cov ntsiab lus ntawm cov ntsev nyob hauv ib lossis ntau qhov ntxiv lossis txo qis