Video: Dab tsi ua rau oxyhemoglobin dissociation nkhaus hloov?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Kev nce siab ntxiv ntawm BPG hauv cov qe ntshav liab nyiam qhov tsim ntawm T, lub xeev qis qis ntawm hemoglobin cov thiab yog li ntawd cov pa - khi nkhaus yuav ua haujlwm mus rau sab xis.
Tom qab ntawd, dab tsi ua rau oxyhemoglobin dissociation nkhaus hloov mus rau sab laug?
Variants nrog nce cov pa kev sib raug zoo ua a hloov mus rau sab laug ntawm nkhaus dissociation oxygen saib (Daim duab 71-2), ua rau tsawg dua cov pa tus me nyuam ib gram ntawm hemoglobin cov . Kom them nyiaj, hemoglobin cov concentration thiab/lossis cov ntshav ntws nce mus rau qee qhov rov qab los cov pa xa mus rau cov ntaub so ntswg.
Zoo sib xws, dab tsi yog qhov cuam tshuam ntawm hypothermia ntawm txoj kab nkhaus kev sib cais oxyhemoglobin? Txo lub cev kub (hypothermia) ua rau sab laug ua haujlwm nyob rau hauv qhov nkhaus kev sib cais oxyhemoglobin, piv txwv li nce hemoglobin kev sib raug zoo rau cov pa, qhov nce ntawm lub cev kub (hyperthermia) ua rau sab xis ua haujlwm , i.e. txo hemoglobin affinity rau oxygen [8].
Yooj yim li ntawd, dab tsi yog qhov nkhaus ntawm kev sib cais oxyhemoglobin qhia rau peb?
Cov oxyhemoglobin dissociation nkhaus (OHDC) qhia txog kev sib raug zoo ntawm cov pa saturation ntawm hemoglobin cov (Soj2) thiab ib nrab siab ntawm cov hlab ntsha cov pa (Pao2). Nws tsis qhia ncaj qha txog cov hlab ntsha hemoglobin cov saturation, ntsuas raws li cov pa saturation los ntawm mem tes oximetry (Spo2).
DPG ntshav yog dab tsi?
oxygen thauj mus los ntshav ….. cov ntshav ), carbon dioxide, thiab 2, 3-diphosphoglycerate (2, 3- DPG ; ntsev hauv liab ntshav cell uas plays lub luag hauj lwm nyob rau hauv liberating oxygen los ntawm hemoglobin cov nyob rau hauv peripheral ncig). Cov tshuaj no tsis khi rau hemoglobin cov ntawm cov chaw sib khi oxygen.
Pom zoo:
Dab tsi yog kev hloov pauv sab laug hauv qhov nkhaus sib cais oxyhemoglobin hu ua?
Cov xwm txheej no hloov pauv lossis hloov pauv qhov nkhaus ntawm kev sib cais oxyhemoglobin. Kev hloov pauv sab xis qhia tias hemoglobin hauv kev tshawb fawb tau txo qis kev nyiam rau oxygen. Kev ua haujlwm sab laug ntawm txoj kab nkhaus yog ib qho cim ntawm hemoglobin kev sib raug zoo ntxiv rau oxygen (piv txwv li ntawm lub ntsws)
Dab tsi ua rau sab laug hloov pauv hauv oxyhemoglobin nkhaus?
Kev ua haujlwm sab laug ntawm txoj kab nkhaus yog ib qho cim ntawm hemoglobin kev sib raug zoo ntxiv rau oxygen (piv txwv li ntawm lub ntsws). fetal hemoglobin muaj O2 siab dua li cov neeg laus hemoglobin; Feem ntau vim qhov txo qis affinity rau 2,3-bisphosphoglycerate
Dab tsi yog qhov oxyhemoglobin dissociation nkhaus qhia peb?
Hauv nws daim ntawv yooj yim tshaj plaws, txoj kab kev sib cais ntawm oxyhemoglobin piav qhia qhov sib piv ntawm ib nrab ntawm cov pa (x axis) thiab cov pa saturation (y axis). Hemoglobin kev sib raug zoo rau cov pa oxygen nce ntxiv raws li cov txheej txheem txuas ntxiv ntawm cov pa oxygen khi
Dab tsi cuam tshuam rau oxygen hemoglobin saturation dissociation nkhaus?
Thaum muaj cov pa roj carbon dioxide yaj, pH ntawm cov ntshav hloov pauv; qhov no ua rau lwm qhov hloov pauv hauv cov duab ntawm hemoglobin, uas ua rau nws muaj peev xwm khi cov pa roj carbon dioxide thiab txo nws lub peev xwm los khi cov pa oxygen
Dab tsi ua rau cov pa oxygen dissociation nkhaus hloov mus rau sab xis?
Qhov nce ntawm qhov kub hloov pauv qhov nkhaus mus rau sab xis, thaum qhov ntsuas kub poob qis hloov txoj kab nkhaus mus rau sab laug. Ua kom qhov kub thiab txias denatures kev sib raug zoo ntawm oxygen thiab hemoglobin, uas ua rau kom cov pa oxygen thiab hemoglobin thiab txo cov concentration ntawm oxyhaemoglobin