Puas yog atropine txwv lossis txhim kho qhov tshwm sim ntawm acetylcholine?
Puas yog atropine txwv lossis txhim kho qhov tshwm sim ntawm acetylcholine?

Video: Puas yog atropine txwv lossis txhim kho qhov tshwm sim ntawm acetylcholine?

Video: Puas yog atropine txwv lossis txhim kho qhov tshwm sim ntawm acetylcholine?
Video: Xov Xwm 03/19/2022: Kev Puas Tsuaj Ntawm Tsov Rog Russia & Ukraine Nrog Rau Ntau Lub Teb Chaws 2024, Lub Xya hli ntuj
Anonim

Koj cov lus teb: Cholingeric thiab adrenergic modifiers txwv , mimic, los yog txhim khu kev ua acetylcholine tshuaj hauv lub cev. Atropine yog acholingeric antagonist uas thaiv cov acetylcholine tshuaj tus neeg txais kev pab nce ntxiv lub plawv dhia. Pilocarpine yog tus coj ncaj qha cholinergic agonist uas txo lub plawv dhia.

Ib yam nkaus, atropine cuam tshuam rau acetylcholine li cas?

A Atropine tshuaj ua los ntawm thaiv cov teebmeem ntawm ntau qhov ntau ntawm acetylcholine tshuaj ntawm muscarinic cholinergic synapses tom qab OP inhibition ntawm AChE. Atropine ua tsis khi rau nicotinic receptors thiab tsis tuaj yeem txo cov teebmeem nicotinic ntawm OPCs.

Tsis tas li, dab tsi receptors ua atropine cuam tshuam? Qhov no tshwm sim vim atropine yog kev sib tw, thim rov qab antagonist ntawm lub muscarinic acetylcholine receptors (cov acetylcholine tshuaj yog lub ntsiab neurotransmitter siv los ntawm parasympathetic paj hlwb). Atropine yog tus yeeb ncuab sib tw ntawm cov muscarinic acetylcholine receptor hom M1, M2, M3, M4 thiab M5.

Ib yam nkaus, puas yog atropine inhibit acetylcholine?

Atropine yog cov tshuaj anticholinergic cuam tshuam nrog chaw kho mob, uas thaiv cov teebmeem cuam tshuam ntawm parasympathetic neurotransmitter acetylcholine tshuaj ntawm lub plawv dhia ua rau tachycardia. Txawm li cas los xij, ntau lub plawv cuam tshuam los ntawm atropine tsis tuaj yeem piav qhia txaus los ntawm nws qhov kev tawm tsam ntawm muscarinic receptors.

Atropine cuam tshuam rau lub plawv ua haujlwm li cas?

Kev siv ntawm atropine hauv plawv teeb meem feem ntau yog hauv kev tswj hwm cov neeg mob nrog bradycardia. Atropine nce lub siab tus nqi thiab txhim kho atrioventricular conduction los ntawm thaiv cov parasympathetic influences rau lub siab.

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