Video: Yuav muaj dab tsi tshwm sim yog tias lub xov tooj ntawm tes hla qib S?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Yog cell tsis tau theej theej nws cov chromosomes lossis muaj kev puas tsuaj rau DNA, CDK yuav tsis qhib S theem cyclin thiab ntawm tes yuav tsis nce mus rau G2 theem . Cov ntawm tes yuav nyob hauv S theem kom txog thaum cov chromosomes raug theej kom raug, lossis cov ntawm tes yuav raug programmed ntawm tes tuag.
Ib yam li ntawd, koj tuaj yeem nug, yuav ua li cas rau lub xov tooj ntawm tes hauv theem S?
Cov S Phase ntawm Interphase The S theem ntawm a ntawm tes Lub voj voog tshwm sim thaum lub sij hawm interphase, ua ntej mitosis los yog meiosis, thiab yog lub luag hauj lwm rau cov synthesis los yog replication ntawm DNA. Lub hom phiaj ntawm cov txheej txheem no yog los tsim ob npaug ntawm DNA, muab lub hauv paus rau chromosome ntawm tus ntxhais. hlwb.
Ib qho ntxiv, cov qog nqaij hlav cancer hla mus rau theem twg? Cov cell nrog DNA tsis tu ncua txuas ntxiv mus S theem ; cov hlwb uas puas DNA uas tsis tuaj yeem kho tau raug ntes thiab "ua tua tus kheej" los ntawm apoptosis, lossis programmed cell tuag. Qhov thib ob qhov chaw kuaj xyuas tshwm sim ntawm theem G2 tom qab qhov synthesis DNA nyob rau hauv S theem tab sis ua ntej faib cell hauv M theem.
Tom qab ntawd, yuav muaj dab tsi tshwm sim yog tias qhov ua yuam kev hauv DNA rov ua dua tshwm sim hauv S theem ntawm lub voj voog ntawm tes?
DNA Replication thiab Checkpoint Control nyob rau hauv S Phase . Lub sijhawm DNA replication , qhov kev tshem tawm ntawm txoj hlua tawm ib txoj hlua yooj yim. Hauv eukaryotic lub voj voog ntawm tes , chromosome duplication tshwm sim thaum " S theem "(cov theem ntawm DNA synthesis) thiab kev sib cais ntawm chromosome tshwm sim thaum "M. theem "(cov mitosis theem ).
Yuav muaj dab tsi tshwm sim rau lub xovtooj yog tias lub chaw kuaj xyuas lub voj voog tsis ua haujlwm zoo?
Yog cov chaw kuaj mob mechanisms ntes teeb meem nrog DNA, lub lub voj voog ntawm tes yog halted thiab ntawm tes sim ua kom tiav DNA replication lossis kho DNA puas. Yog DNA tau ua yog lawm replicated, cyclin dependent kinases (CDKs) qhia qhov pib ntawm mitotic cell faib.
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