Dab tsi yog glycosaminoglycans ua los ntawm?
Dab tsi yog glycosaminoglycans ua los ntawm?

Video: Dab tsi yog glycosaminoglycans ua los ntawm?

Video: Dab tsi yog glycosaminoglycans ua los ntawm?
Video: Qhov Ntawm Ko Yog Dab Tsi 2024, Lub Xya hli ntuj
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Glycosaminoglycans (GAGs) los yog mucopolysaccharides yog ntev linear polysaccharides muaj xws li rov ua dua disaccharide (ob npaug qab zib ) units. Tsuas yog keratin, chav tsev rov ua dua muaj cov suab thaj amino, nrog rau cov suab thaj uronic lossis galactose.

Kuj nug, qhov twg glycosaminoglycans pom hauv lub cev?

Proteoglycans. Proteoglycans (mucoproteins) yog tsim los ntawm cov glycosaminoglycans ( GAGs ) covalently txuas rau cov protein tseem ceeb. Lawv yog pom nyob rau hauv tag nrho cov ntaub so ntswg sib txuas, cov txheej txheem txuas ntxiv (ECM) thiab ntawm cov npoo ntawm ntau hom cell.

Ib qho ntxiv, qhov piv txwv ntawm glycosaminoglycan yog dab tsi? Lub physiological zog ntawm proteoglycans yog ib qho kev ua haujlwm ntawm qhov tshwj xeeb cov glycosaminoglycans tam sim no. Piv txwv ntawm ntau cov glycosaminoglycans chondroitin 6-sulfate, keratan sulfate, heparin, dermatan sulfate, thiab hyaluronate. Piv txwv ntawm proteoglycans suav nrog Versican, Brevican, Neurocan, thiab Aggrecan.

Xav txog qhov no, GAGs ua los ntawm dab tsi?

GAGs yog polysaccharide chains ua los ntawm rov ua dua hyaluronic acid – hexosamine units ib txwm txuas rau cov protein ntau, yog li tsim cov proteoglycans.

GAGs tsim nyob qhov twg?

GAGs nyob rau hauv feem ntau ntawm cov hlwb los yog nyob rau hauv lub extracellular matrix (ECM) tab sis kuj muaj nyob rau hauv secretory vesicles nyob rau hauv ib co hom cell.

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