Video: Metyrapone siv rau dab tsi?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Metyrapone , muag raws li lub npe tshuaj Metopirone, yog tshuaj uas yog siv hauv kev kuaj mob ntawm adrenal tsis txaus thiab qee zaum hauv kev kho Cushing's syndrome (hypercortisolism).
Ua kom pom qhov no, Metopirone siv rau dab tsi?
Siv ntawm Metopirone : Nws yog siv txhawm rau txheeb xyuas cov qog ua haujlwm hauv lub caj pas. Tej zaum nws yuav muab rau koj rau lwm yam laj thawj.
Qhov thib ob, kev ntsuas metyrapone yog dab tsi? Cov metyrapone kev txhawb nqa xeem yog ua raws lub hauv paus ntsiab lus uas txo qis cov ntshav cortisol ntau ntau ib txwm ua rau nce hauv corticotropin (ACTH) tso tawm vim qhov txo qis hauv glucocorticoid cov lus pom tsis zoo. Cov xeem tau ua tiav feem ntau txhawm rau txheeb xyuas qhov tsis xws luag hauv pituitary ACTH tso tawm.
Ua li no, Ntev npaum li cas Metyrapone ua haujlwm?
Metyrapone yog sai absorbed thiab tshem tawm los ntawm cov ntshav. Cov ntshav ntshav feem ntau tshwm sim ib teev tom qab noj Metopirone; tom qab a koob tshuaj 750 mg Metopirone, cov tshuaj ntshav qib nruab nrab 3.7Μg/ml. Cov tshuaj plasma qib qis rau a Tus nqi nruab nrab ntawm 0.5Μg / ml 4 teev tom qab noj.
Ketoconazole kho Cushing's li cas?
Ketoconazole muaj txiaj ntsig zoo rau kev tswj lub sijhawm ntev ntawm hypercortisolism ntawm pituitary lossis adrenal keeb kwm. Nws cov txiaj ntsig tau tshwm sim los ntawm kev cuam tshuam ntawm adrenal 11 beta-hydroxylase thiab 17, 20-lyase, thiab nws, hauv qee txoj kev tsis paub, tiv thaiv kev cia siab nce hauv ACTH tso tawm hauv cov neeg mob nrog Cushing cov kab mob.
Pom zoo:
Kev ntsuas metyrapone yog dab tsi?
Kev ntsuas kev txhawb nqa metyrapone yog ua raws txoj hauv kev uas txo qis cov ntshav cortisol ntau ntau ua rau muaj kev nce ntxiv hauv corticotropin (ACTH) vim yog txo qis hauv glucocorticoid cov lus tsis zoo. Qhov kev sim no feem ntau yog txhawm rau txheeb xyuas qhov tsis xws luag hauv pituitary ACTH tso tawm
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