Muaj pes tsawg tus sglt2 inhibitors muaj?

2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44

Tam sim no muaj yog peb SGLT2 xaiv inhibitors Kev pom zoo los ntawm Food and Drug Administration (FDA) rau mono, dual, thiab triple therapy: canagliflozin (Invokana®), dapagliflozin (Farxiga®) thiab empagliflozin (Jardiance®) (5, 11, 12).

Raws li, cov npe ntawm sglt2 inhibitors yog dab tsi?

Hom thiab cov npe ntawm SGLT2 inhibitors thiab cov khoom sib xyaw ua ke uas muaj SGLT2 inhibitors suav nrog:

• Canagliflozin (Invokana)
• Canagliflozin / Metformin (Invokamet)
• canagliflozin/metformin ncua kev tso tawm (Invokamet XR)
• dapagliflozin (Farxiga)
• dapagliflozin/metformin ncua kev tso tawm (Xigduo XR)

Ib yam li ntawd, sglt2 inhibitors siv li cas? Cov tshuaj no ua haujlwm los ntawm kev tiv thaiv cov piam thaj los ntawm kev nqus hauv lub raum. Yog li ntawd, lawv txo cov piam thaj hauv cov ntshav thiab ua rau nws ntws mus rau hauv cov zis. Thaum twg? Txoj kev kho mob yuav txawv rau txhua tus neeg, tab sis feem ntau SGLT2 cov tshuaj tiv thaiv kab mob noj ib zaug ib hnub ua ntej thawj pluas noj.

Ntawm no, puas yog Metformin ib qho sglt2 inhibitors?

SGLT2 cov tshuaj tiv thaiv kab mob yog chav kawm ntawm cov tshuaj kws tshuaj pom zoo rau siv nrog kev noj zaub mov thiab tawm dag zog kom txo cov ntshav qab zib hauv cov neeg laus uas muaj ntshav qab zib hom 2. Lawv muaj raws li cov khoom lag luam ib leeg thiab tseem ua ke nrog lwm yam tshuaj kho ntshav qab zib xws li metformin tshuaj (saib FDA pom zoo SGLT2 Inhibitors ).

Puas yog januvia yog sglt2 inhibitor?

Kev sib xyaw ntawm DPP-4 inhibitors thiab SGLT2 cov tshuaj tiv thaiv kab mob ua rau muaj nqi kho mob siab dua tab sis tseem nce tag nrho QALYs los ntawm 0.24. Merck muag DPP-4 sitagliptin inhibitor ( Januvia ). Merck kuj muag ua ke DPP-4/ SGLT2 inhibitor , sitagliptin tshuaj /ertugliflozin (Steglujan).