Cov txheej txheem:
Video: Tus alpha 2 agonist ua haujlwm li cas?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Alpha 2 receptors nyob rau hauv lub paj hlwb thiab nyob ib puag ncig cuam tshuam kev ua siab zoo thiab yog li ua rau cov ntshav siab. Alpha 2 tus txais agonists xws li clonidine lossis guanabenz txo qis hauv nruab nrab thiab cov khoom nruab nrog sab nruab nrog cev thiab dhau ntawm cov khoom siv ib puag ncig presynaptic cov receptors yuav txo qis kev tso tawm cov hlab ntsha ib leeg.
Ua kom pom qhov no, alpha 2 agonist ua dab tsi?
α 2 agonist : txwv tsis pub ua haujlwm adenylyl cyclase, txo qis kev ua haujlwm ntawm vasomotor nruab nrab-nruab nrab CNS ua kom; siv raws li antihypertensive, sedative & kev kho mob ntawm kev quav yeeb quav tshuaj thiab cov tsos mob tshem tawm cawv).
Qhov thib ob, puas yog Alpha 2 ua rau vasoconstriction? Lub luag hauj lwm ntawm cov alpha ( 2 ) -AR tsev neeg tau paub ntev los suav nrog presynaptic inhibition ntawm kev tso tawm cov tshuaj xa mus rau lub cev, txo qis kev nkag siab zoo ntawm cov tsheb khiav mus los, vasodilation thiab vasoconstriction . Cov lus teb nyuaj no tau kho kom haum xeeb los ntawm ib ntawm peb hom subtypes uas txhua qhov tshwj xeeb cuam tshuam rau ntshav siab thiab ntshav ntws.
Tom qab ntawd, lo lus nug yog, yuav ua li cas alpha 2 agonists ua rau sedation?
Sedative teebmeem Alpha2 - agonists khi nrog thiab intrinsically hloov cov membranes ntawm lub α2 -adrenoreceptors, tiv thaiv kev tso tawm ntxiv ntawm cov neurotransmitter norepinephrine. Hauv nruab nrab, norepinephrine yog qhov tsim nyog rau kev txhawb siab. Yog tias qhov tso tawm ntawm norepinephrine raug thaiv, qhov txiaj ntsig tau yog sedation.
Cov tshuaj twg yog lub hauv paus alpha 2 agonists?
Alpha-2 agonists
- Clonidine (Catapres®)
- Clonidine thaj (Catapres-TTS®)
- Methyldopa (Aldomet®)
- Tizanidine (Zanaflex®) - siv los ua cov leeg nqaij.
- Clonidine (Kapvay®) - siv los kho ADHD.
- Guanfacine (Intuniv®) - siv los kho ADHD.
- Lofexidine (Lucemyra ™) - FDA tau pom zoo los kho kev quav yeeb quav tshuaj.
Pom zoo:
Alpha 2 agonist ua dab tsi?
Α2 agonist: inhibits adenylyl cyclase kev ua, txo lub paj hlwb vasomotor nruab nrab nruab nrab CNS ua kom; siv raws li antihypertensive, sedative & kev kho mob ntawm kev quav yeeb quav tshuaj thiab cov tsos mob tshem tawm cawv)
Tus txiv neej ua haujlwm ua haujlwm li cas?
Cov txiv neej lub cev sib deev ua haujlwm ua ke los tsim thiab tso cov phev rau hauv cov poj niam lub cev thaum sib deev. Tus txiv neej ua haujlwm hauv lub cev kuj tseem tsim cov tshuaj hormones poj niam txiv neej, uas pab tus tub txhim kho mus ua txiv neej txiv neej deev thaum tseem hluas. Thaum lub sij hawm no, ib tug me nyuam tub lub suab kuj tob
Tus neeg saib xyuas chav ua haujlwm ua haujlwm li cas?
Lub Sij Hawm Lub Sijhawm Teem sijhawm teem sijhawm rau cov neeg mob rau kev phais. Saib xyuas chav ua haujlwm, teem sijhawm kws phais neeg, thiab cov neeg pab xav tau rau txheej txheem. Ua Tus Neeg Ua Haujlwm Chav Teem Sijhawm sau thiab sau cov ntaub ntawv nyiaj txiag thiab pov hwm. Faib cov ntaub ntawv ua ntej thiab tom qab ua haujlwm rau cov neeg mob
Lub luag haujlwm ntawm tus kws saib xyuas mob plawv tsis ua haujlwm yog dab tsi hauv kev saib xyuas cov neeg mob plawv tsis ua haujlwm?
Raws li ib feem ntawm pab pawg, tus kws kho mob lub plawv tsis ua haujlwm tau zoo muab rau muab kev pabcuam rau cov neeg mob thoob plaws txoj kev mob plawv tsis ua haujlwm thiab qhov no yuav tsum muaj kev koom tes ze nrog kws saib xyuas mob hauv thaj chaw tshwj xeeb tshwj xeeb xws li chav kho mob xwm txheej ceev thiab kev kho mob dav/ saib xyuas-ntawm-tus-neeg laus
Puas yog Xylazine yog alpha 2 agonist?
Alpha-2 agonists muab sedation, analgesia, nqaij so thiab anxiolysis. Ntau yam sib xyaw tau tsim los siv rau tib neeg thiab tshuaj kho tsiaj, suav nrog clonidine, romifidine, detomidine, xylazine, medetomidine, thiab dexmedetomidine