Video: Dab tsi yog qhov kev hloov pauv uas ua rau mob qog nqaij hlav anemia?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Sickle cell kab mob yog ua los ntawm a kev hloov pauv nyob rau hauv hemoglobin-Beta noob pom ntawm chromosome 11. Hemoglobin thauj oxygen los ntawm lub ntsws mus rau lwm qhov hauv lub cev. Ntshav liab hlwb Nrog ib txwm hemoglobin (hemoglobin-A) yog du thiab puag ncig thiab glide los ntawm cov hlab ntsha.
Tsuas yog li ntawd, hom kev hloov pauv twg yog lub luag haujlwm rau mob qog ntshav ntshav ntshav?
Siav - cell ntshav tsis txaus yog tshwm sim los ntawm tus taw tes kev hloov pauv hauv chain-globin saw ntawm hemoglobin, ua rau hydrophilic amino acid glutamic acid hloov pauv nrog hydrophobic amino acid valine ntawm txoj haujlwm thib rau. Lub β-globin noob muaj nyob rau ntawm caj npab luv ntawm chromosome 11.
Dab tsi ua rau mob kab mob ntshav qab zib? Sickle cell anemia yog ua los ntawm kev hloov pauv hauv cov noob uas qhia koj lub cev kom ua rau cov hlau sib xyaw uas ua rau cov ntshav liab thiab ua rau cov ntshav liab hlwb nqa oxygen los ntawm koj lub ntsws thoob plaws hauv koj lub cev (hemoglobin).
Raws li, qhov hloov pauv DNA dab tsi ua rau mob ntshav tsis txaus?
Sickle cell anemia yog tshwm sim los ntawm ib tsab ntawv hloov pauv hauv DNA. Qhov no nyob rau hauv lem hloov ib yam ntawm cov cov amino acids hauv hemoglobin protein ntau . Valine zaum hauv qhov chaw uas glutamic acid yuav tsum yog.
Kev hloov pauv uas ua rau cov ntshav tsis muaj ntshav cuam tshuam li cas rau cov qauv hemoglobin?
Cov kev hloov pauv hauv HBB noob hauv sickle cell anemia hloov ib qho ntawm cov amino acids, lub tsev blocks ntawm cov proteins, nyob rau hauv beta saw ntawm hemoglobin . Qhov tsis xws luag no ua cov hemoglobin cov protein kom lo ua ke thiab tsim cov fibers tawv. Cov fibers no cuam tshuam cov duab ntawm cov ntshav liab hlwb thiab ua rau lawv tawg yooj yim dua.
Pom zoo:
Yuav ua li cas feem pua ntawm cov qog nqaij hlav qog nqaij hlav qog noj ntshav?
Kev Kho Mob: Kev kho hluav taws xob
Yam twg ntawm cov hauv qab no yog qhov hloov pauv hloov pauv tau rau kev mob pob txha?
Yam yuav hloov pauv tau yam muaj xws li: Dej cawv. Kev haus luam yeeb. Low Body Mass Index. Kev noj zaub mov tsis zoo. Vitamin D tsis txaus. Kev noj zaub mov tsis zoo. Estrogen tsis muaj peev xwm. Kev tawm dag zog tsis txaus
Kev sib raug zoo ntawm kev hloov pauv thiab kev nug txog mob qog noj ntshav yog dab tsi?
Mob qog noj ntshav yog kab mob uas cov cell faib tsis tau tswj hwm. Qee cov noob tsim cov qauv, qee cov txheej txheem tswj. Cancer tshwm sim los ntawm kev hloov pauv uas cuam tshuam kev sib txuas ntawm mitosis. Cells txuas ntxiv tsim cov qog nqaij hlav
Cov kab mob dab tsi yog txuas nrog kev hloov pauv ntawm cov qog nqaij hlav qog ntshav?
Kev hloov pauv ntawm ob lwm cov qog qog ua qog, BRCA1 thiab BRCA2, yog lub luag haujlwm rau cov kab mob qog noj ntshav ntawm lub mis, uas suav txog 5 txog 10% ntawm tag nrho cov mob qog noj ntshav mis
Puas yog cov qog nqaij hlav qog nqaij hlav nyuaj?
Shotty feem ntau siv los piav txog qhov kev xav ntawm cov qog nqaij hlav (cov qog qog nqaij hlav) thaum lawv palpated (xws li) los ntawm daim tawv nqaij. 'Shotty' lymph nodes yog cov uas tsis yog nyuaj thiab puag ncig tab sis kuj me me thiab tsis muaj qhov tshwm sim