Video: Dab tsi yog qhov oxyhemoglobin dissociation nkhaus qhia peb?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Hauv nws daim ntawv yooj yim tshaj plaws, lub oxyhemoglobin dissociation nkhaus piav qhia txog kev sib raug zoo ntawm ib nrab siab ntawm oxygen (x axis) thiab oxygen saturation (y axis). Cov hemoglobin affinity rau oxygen nce raws li successive molecules ntawm oxygen khi.
Kuj tseem paub yog, vim li cas oxyhemoglobin dissociation nkhaus tseem ceeb?
Feem ntau tseem ceeb factor hauv tus nqi ntawm oxygen uas khi (txuas) rau hemoglobin molecules yog ib nrab siab ntawm arterial oxygen (Pao2); qhov siab dua, qhov yooj yim dua oxygen ua ke nrog hemoglobin hauv cov ntshav liab. Qhov no hemoglobin - oxygen kev sib txuas hu ua oxyhemoglobin.
Tsis tas li ntawd, dab tsi yog qhov cuam tshuam ntawm hypothermia ntawm txoj kab nkhaus kev sib cais oxyhemoglobin? Kev txo lub cev kub (hypothermia) ua rau sab laug ua haujlwm nyob rau hauv qhov nkhaus kev sib cais oxyhemoglobin, piv txwv li nce hemoglobin kev sib raug zoo rau cov pa, qhov nce ntawm lub cev kub (hyperthermia) ua rau sab xis ua haujlwm , i.e. txo hemoglobin affinity rau oxygen [8].
Ib yam li ntawd, tib neeg nug, dab tsi yog txoj haujlwm hloov pauv hauv cov pa oxygen hemoglobin nkhaus nkhaus qhia rau peb?
Cov cov pa oxygen sib cais tau ua hloov txoj cai los yog sab laug los ntawm ntau yam. A txoj cai hloov qhia tau tias txo oxygen affinity ntawm hemoglobin tso cai ntxiv oxygen kom muaj rau cov ntaub so ntswg. A sab laug ua haujlwm qhia tias nce oxygen affinity ntawm hemoglobin tso cai tsawg dua oxygen kom muaj rau cov ntaub so ntswg.
Dab tsi hloov pauv qhov oxyhemoglobin nkhaus nkhaus mus rau sab laug?
Variants nrog nce oxygen affinity ua rau a ua haujlwm mus rau sab laug ntawm cov pa oxygen dissociation nkhaus saib (Daim duab 71-2), ua rau cov pa oxygen tsawg dua ib gram ntawm hemoglobin. Txhawm rau them nyiaj, hemoglobin concentration thiab / lossis ntshav ntws nce txhawm rau rov kho cov pa oxygen mus rau cov ntaub so ntswg.
Pom zoo:
Dab tsi yog kev hloov pauv sab laug hauv qhov nkhaus sib cais oxyhemoglobin hu ua?
Cov xwm txheej no hloov pauv lossis hloov pauv qhov nkhaus ntawm kev sib cais oxyhemoglobin. Kev hloov pauv sab xis qhia tias hemoglobin hauv kev tshawb fawb tau txo qis kev nyiam rau oxygen. Kev ua haujlwm sab laug ntawm txoj kab nkhaus yog ib qho cim ntawm hemoglobin kev sib raug zoo ntxiv rau oxygen (piv txwv li ntawm lub ntsws)
4 yam nkhaus nkhaus ntawm tus nqaj qaum yog dab tsi?
Cov pob txha no, hu ua vertebrae, tau muab faib ua tsib thaj chaw: ncauj tsev menyuam, thoracic, lumbar, sacral, thiab coccyx. Txawm hais tias tus nqaj qaum ua rau peb sawv ntsug ncaj, tus qauv yog dab tsi tab sis. Muaj tiag peb qhov nkhaus nkhaus ntawm tus nqaj qaum (plaub yog tias koj suav tus pob tw)
Dab tsi ua rau oxyhemoglobin dissociation nkhaus hloov?
Kev nce siab ntxiv ntawm BPG hauv cov qe ntshav liab nyiam qhov tsim ntawm T, qis qis hauv lub xeev ntawm hemoglobin thiab yog li cov pa nkev-khi nkhaus yuav hloov mus rau sab xis
Dab tsi yog 2/3 DPG oxygen dissociation nkhaus?
2,3-BPG ua raws li heteroallosteric effector hemoglobin, txo qis hemoglobin kev sib raug zoo rau cov pa oxygen los ntawm kev khi tshwj xeeb rau deoxyhemoglobin. Kev nce siab ntxiv ntawm BPG hauv cov qe ntshav liab nyiam qhov tsim ntawm T, qis qis hauv lub xeev ntawm hemoglobin thiab yog li cov pa nkev-khi nkhaus yuav hloov mus rau sab xis
Dab tsi ua rau sab laug hloov pauv hauv oxyhemoglobin nkhaus?
Kev ua haujlwm sab laug ntawm txoj kab nkhaus yog ib qho cim ntawm hemoglobin kev sib raug zoo ntxiv rau oxygen (piv txwv li ntawm lub ntsws). fetal hemoglobin muaj O2 siab dua li cov neeg laus hemoglobin; Feem ntau vim qhov txo qis affinity rau 2,3-bisphosphoglycerate