Video: Alpha 2 agonists ua dab tsi?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
α2 agonist : txwv tsis pub ua haujlwm adenylyl cyclase, txo cov hlab ntsha vasomotor nruab nrab-nruab nrab CNS ua kom; siv raws li antihypertensive, sedative & kev kho mob ntawm kev quav yeeb quav tshuaj thiab cov tsos mob tshem tawm cawv).
Ntawm no, alpha 2 agonist tshuaj yog dab tsi?
Alpha - 2 cov agonists . Clonidine (Catapres®) Clonidine thaj (Catapres -TTS®) Methyldopa (Aldomet®) Tizanidine (Zanaflex®) - siv los ua leeg nqaij.
Ib sab saum toj, ua li cas alpha 2 agonists ua rau sedation? Sedative teebmeem Alpha2 - agonists khi nrog thiab intrinsically hloov cov membranes ntawm lub α2 -adrenoreceptors, tiv thaiv kev tso tawm ntxiv ntawm cov neurotransmitter norepinephrine. Hauv nruab nrab, norepinephrine yog qhov tsim nyog rau kev txhawb siab. Yog tias qhov tso tawm ntawm norepinephrine raug thaiv, qhov txiaj ntsig tau yog sedation.
Tom qab ntawd, tus neeg txais alpha 2 ua dab tsi?
Alpha 2 receptors nyob rau hauv lub paj hlwb thiab nyob ib puag ncig cuam tshuam kev ua siab zoo thiab yog li ua rau cov ntshav siab. Alpha 2 tus neeg txais agonists xws li clonidine lossis guanabenz txo qis hauv nruab nrab thiab cov khoom nruab nrog sab nruab nrog cev thiab dhau ntawm cov khoom siv ib puag ncig presynaptic cov receptors yuav txo qis kev tso tawm cov hlab ntsha ib leeg.
Qhov txawv ntawm alpha 1 thiab alpha 2 receptors yog dab tsi?
Alpha 1 receptors yog cov classic postsynaptic alpha receptors thiab muaj nyob rau ntawm vascular du nqaij. Lawv txiav txim siab ob qho kev tiv thaiv arteriolar thiab cov leeg ntshav, thiab yog li BP. Alpha 2 receptors pom ob leeg hauv hlwb thiab hauv ib puag ncig. Hauv lub paj hlwb qia, lawv modulate sympathetic outflow.
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Cov tshuaj twg yog alpha 2 agonists?
Alpha-2 agonists Clonidine (Catapres®) Clonidine thaj (Catapres-TTS®) Methyldopa (Aldomet®) Tizanidine (Zanaflex®) - siv los ua cov leeg nqaij. Clonidine (Kapvay®) - siv los kho ADHD. Guanfacine (Intuniv®) - siv los kho ADHD. Lofexidine (Lucemyra ™) - FDA pom zoo los kho opiate rho tawm